Research Article
Topical Application of bFGF Alone for the Regeneration of Chronic Tympanic Membrane Perforations: A Preliminary Case Series
| | Side | Age, years | Sex | Duration, years | Size | Position | Etiology | Myringosclerosis | History of otorrhoea? | Pretreatment PTA (dBHL) | Posttreatment PTA (dBHL) | Follow-up | Successful? | Decrease of size |
| | Patient 1 | L | 37 | F | 11 | Medium | Anterosuperior | COM | No | Yes | 27.25 | 27.25 | 3 months | No | Unchanged | | Patient 2 | L | 54 | F | 31 | Medium | Anteroinferior | COM | Yes | Yes | 30 | 22.5 | 6 months | No | Decrease 20% | | Patient 3 | R | 48 | F | 19 | Medium | Anteroinferior | COM | No | Yes | 22.25 | 22.25 | 3 months | No | Unchanged | | Patient 4 | R | 61 | F | 34 | Small | Anteroinferior | COM | No | Yes | 16.25 | 16.0 | 3 months | No | Unchanged | | Patient 5 | L | 54 | M | 49 | Small | Anteroinferior | COM | No | Yes | 12.5 | 12.5 | 4 weeks | Yes | Closure | | Patient 6 | R | 48 | M | 8 | Small | Anteroinferior | COM | No | Yes | 18.25 | 12.0 | 4 weeks | Yes | Closure | | Patient 7 | R | 51 | M | 12 | Medium | Anteroinferior | COM | No | Yes | 17.5 | 15.0 | 3 months | No | Decrease10% | | Patient 8 | R | 39 | M | 1.5 | Medium | Anteroinferior | Trauma | No | No | 22.5 | 12.25 | 4 weeks | Yes | Closure | | Patient 9 | L | 55 | M | 3 | Medium | Anteroinferior | Trauma | No | No | 27.5 | 10.5 | 2 weeks | Yes | Closure | | Patient 10 | R | 47 | F | 9 | Small | Anteroinferior | COM | No | Yes | 12.5 | 12.25 | 3Weeks | Yes | Closure | | Patient 11 | R | 49 | M | 26 | Small | Anteroinferior | COM | No | Yes | 16.0 | 16.0 | 3 months | No | Decrease30% | | Patient 12 | R | 48 | F | 13 | Small | Anteroinferior | COM | Yes | Yes | 17.25 | 5.0 | 8 weeks | Yes | Closure | | Patient 13 | R | 39 | F | 7 | Medium | Anteroinferior | COM | No | Yes | 20.25 | 20.5 | 3 months | No | Unchanged |
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L: Left; R: Right; F: Female; M: Male; COM: chronic otitis media; PTA: Pure-tone audiometry.
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