Research Article

Electrophysiological Changes of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes during Acute Hypoxia and Reoxygenation

Figure 5

Field potential propagation (FPP) through the hiPSC-CM sheet during baseline, hypoxia, and reoxygenation. (a) Propagation of the FP the hiPSC-CM sheet on the MEA electrodes during baseline and different hypoxia and reoxygenation timepoints. (b) Hypoxia significantly increased the FPP time calculated between adjacent electrodes, whereas reoxygenation decreased it. However, even at the end of the reoxygenation period, the FPP remains increased compared to the baseline. , , and .
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