Research Article
Immunization with Embryonic Stem Cells/Induced Pluripotent Stem Cells Induces Effective Immunity against Ovarian Tumor-Initiating Cells in Mice
Figure 5
Vaccination with lysates of mESCs/mIPSCs induced significantly higher protective immunity against CSCs-derived tumors than controls in vivo. (a) Image of the tumors harvested from mice in all groups. (b, c) The tumor volume of mice immunized with mESCs/mIPSCs-based vaccine was significantly smaller compared with the control groups (indicates compared to MEFs + CpG or PBS + CpG group, n = 6, error bars represent SD, one-way ANOVA).
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