[Retracted] Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway

<div>SW480/oxaliplatin exosomes are enriched in BMP-2, which improve angiogenesis via the inhibition of the Smad signaling pathway. HUVECs were co-cultured with SW480/oxaliplatin exosomes (40 <i>μ</i>g/mL) with or without the treatment of si-RNA. (a) The expression of BMP-2 in exosomes. (b) Proliferation assay of HUVECs. (c) The Transwell assay determined the HUVECs migration. (d) The expression of CD31 detected by immunofluorescence. (e) The protein expression of VEGF and phosphorylation Smad5 in HUVECs. 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Applied Bionics and Biomechanics

fig5

Figure 5

Figure 5: [Retracted] Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway 