Review Article
[Retracted] Advances in the Study of Inhaled Formulations for the Treatment of Pulmonary Arterial Hypertension
Table 1
The inhalation drugs and their function to treat PAH.
| Inhalation drugs | Function |
| Prostacyclin analogues | Stabilize role in maintaining the system of the intravascular environment | Nitric oxide | Inhibit platelet aggregation, smooth muscle cell proliferation | Soluble guanylate cyclase (sGC) agonist | Catalyze the formation of cGMP | PDE inhibitors | Regulate their hydrolysis in the cell | Rho kinase inhibitors | Mediate a series of phosphorylation reactions of their downstream effectors | Vasoactive intestinal peptide | Diastole smooth muscle cells and antiproliferative effects | Adrenomedullin | Inhibit smooth muscle proliferation and migration |
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