Research Article

[Retracted] High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein

Table 3

Toxicity analysis of the shortlisted four compounds.

NameMax. tolerated dose (human)Minnow toxicityT. Pyriformis toxicityOral rat acute toxicity (LD50)Ames testHepatotoxicSkin sensitization

NPA000018−0.265−2.360.2852.919NoNoNo
NPA000111−0.5880.4610.3112.625NoYesNo
NPA000305−1.679.580.282.58NoNoNo
NPA014826−0.1472.660.2932.393NoYesNo