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Applied Bionics and Biomechanics
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Applied Bionics and Biomechanics
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2022
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Article
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Tab 3
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Research Article
[Retracted] High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein
Table 3
Toxicity analysis of the shortlisted four compounds.
Name
Max. tolerated dose (human)
Minnow toxicity
T
.
Pyriformis
toxicity
Oral rat acute toxicity (LD50)
Ames test
Hepatotoxic
Skin sensitization
NPA000018
−0.265
−2.36
0.285
2.919
No
No
No
NPA000111
−0.588
0.461
0.311
2.625
No
Yes
No
NPA000305
−1.67
9.58
0.28
2.58
No
No
No
NPA014826
−0.147
2.66
0.293
2.393
No
Yes
No