Inadvertent Transfer of Murine VL30 Retrotransposons to CAR-T Cells
Table 8
Sequence homologies between various VL30 genomes and the human genome. The Genome Browser of the University of California Santa Cruz Genomic Institute (https://genome.ucsc.edu/) was employed to identify sequence homologies between various VL30 genomes and the human genome. The accession numbers associated with the sequence of the various VL30 genomes, which were employed in the VL30/human sequence homology screen, are indicated. The positions of the first and last (start and end, respectively) of VL30 nucleotides in the homologous sequence are shown. VL30 nucleotides that matched their respective nucleotides in homologous human sequences are shown in capital letters. The chromosome number of human chromosomes containing sequences with homology to VL30 genome sequences is indicated. The orientations of the relevant homologous strands are shown. The positions of the first and last (start and end, respectively) nucleotides in the human chromosomes with homology to the relevant VL30 sequence are shown. The repetitive sequences in the human chromosomes with homology to the abovementioned VL30 genomes are defined.