Expression of EGFR and Molecules Downstream to PI3K/Akt, Raf-1-MEK-1-MAP (Erk1/2), and JAK (STAT3) Pathways in Invasive Lung Adenocarcinomas Resected at a Single Institution

<div>Immunohistochemical findings of different markers in lung adenocarcinomas. (a) EGFR positive acinar predominant tumor showing both distinct membranous and cytoplasm expression. (b) High power of EGFR positive solid predominant adenocarcinoma. (c) TTF-1 positive acinar tumor. (d) High power of STAT3 positive tumor with intense cytoplasm positivity. (e) ERCC1 positive lepidic predominant tumor, with intense nuclear positivity. (f) ERK1/2 expression in solid tumor showing both nuclear and cytoplasm reactivity.</div>

Analytical Cellular Pathology

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Figure 2

Figure 2: Expression of EGFR and Molecules Downstream to PI3K/Akt, Raf-1-MEK-1-MAP (Erk1/2), and JAK (STAT3) Pathways in Invasive Lung Adenocarcinomas Resected at a Single Institution 

Figure 2 | Expression of EGFR and Molecules Downstream to PI3K/Akt, Raf-1-MEK-1-MAP (Erk1/2), and JAK (STAT3) Pathways in Invasive Lung Adenocarcinomas Resected at a Single Institution 