Research Article

High Percentage of ADAM-10 Positive Melanoma Cells Correlates with Paucity of Tumor-Infiltrating Lymphocytes but Does Not Predict Prognosis in Cutaneous Melanoma Patients

Table 2

Histopathological parameters of primary tumors.

Histopathological parameters of the primary tumorNumber (%)

Breslow thickness
34 (32.7)
 1.01–2.00 mm20 (19.2)
 2.01–4.00 mm27 (26.0)
23 (22.1)
Clark level
 I0 (0.0)
 II18 (17.3)
 III49 (47.1)
 IV26 (25.0)
 V11 (10.6)
Histologic type
 Superficial spreading melanoma (SSM)68 (65.4)
 Nodular malignant melanoma (NMM)32 (30.8)
 Acral-lentiginous melanoma (ALM) 4 (3.8)
Mitotic rate
 045 (43.3)
 1-226 (25.0)
 ≥333 (31.7)
Ulceration
 No55 (52.9)
 Yes49 (47.1)
Lymphangio invasion
 No74 (71.2)
 Yes30 (28.8)
Growth phase
 Radial3 (2.9)
 Vertical101 (97.1)
Tumor-infiltrating lymphocytes (TILs)
 No18 (17.3)
 Nonbrisk34 (32.7)
 Brisk52 (50)
Microsatellitosis 
 No98 (94.2)
 Yes6 (5.8)
Tumor regression 
 No96 (92.3)
 Yes8 (7.7)