Long Noncoding RNA MIR4697HG Promotes Cell Growth and Metastasis in Human Ovarian Cancer

Figure 5

Knockdown of MIR4697HG inhibits cell migration and invasion in SKOV3 cells and OVCAR3 cells. (a) Both SKOV3 cells and OVCAR3 cells with (shRNA group) or without (NC group) specific shRNA transfections were subject to transwell migration and invasion assays. The transmigrated cells underneath the membrane were stained with crystal violet and photographed under a light microscopy. Five representative images were randomly selected for each group. (b) Invaded cells were counted in both SKOV3 cells and OVCAR3 cells with MIR4697HG knockdown (shRNA group) or not (NC group). Data were collected from five randomly selected fields and averaged for each group. (c) Migrated cells were counted in both SKOV3 cells and OVCAR3 cells with MIR4697HG knockdown (shRNA group) or not (NC group). Data were collected from five randomly selected fields and averaged for each group. .

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