Schistosoma Egg Antigen Induces Oncogenic Alterations in Human Prostate Cells

Figure 4

schSEA diminishes apoptosis in PNT2 cells. (a) (A) Negative control, (B) 6.25 μg/ml schSEA, (C) 12.5 μg/ml schSEA, and (D) serum-fed (positive control). Lower left quadrant: viable cells; lower right quadrant: early apoptotic cells; upper left quadrant: nuclear debris; upper right quadrant: late apoptotic cells. Data was acquired by Guava EasyCyte™ flow cytometer. (b) Comparison of apoptosis and cell viability among various experimental groups. Statistical significance by Student’s -test: (serum-fed vs. serum-starved/schSEA-treated groups). Results are representative of three independent experiments.

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