Research Article
PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer
Figure 6
Knockdown of PAK5 inactivated the PI3K/AKT pathway. The phosphorylation levels of PI3K p83 at Tyr458 (p-PI3K p85 at Tyr458) and phosphorylation levels of AKT at Ser473 and Thr308 were detected. The total protein levels of AKT and PI3K p85 were also determined.