Research Article

PD-L1 Immunohistochemistry Comparability and Their Correlation with Clinical Characteristics in NSCLC

Table 1

Baseline characteristics.

Characteristics (%)

Age, median (range in years)65 (28-94)
 ≤6573 (50.7%)
 >6571 (49.3%)
Gender
 Male92 (63.9%)
 Female52 (36.1%)
Histology
 Adenocarcinoma101 (70.1%)
 Squamous cell carcinoma19 (13.2%)
 Adenosquamous carcinoma5 (3.5%)
 NSCLC19 (13.2%)
T ()
 19 (6.7%)
 225 (18.5%)
 322 (16.3%)
 479 (58.5%)
N
 013 (9.0%)
 111 (7.6%)
 230 (20.8%)
 390 (62.5%)
M
 024 (16.7%)
 1120 (83.3%)
Stage
 I/II6 (4.2%)
 III18 (12.5%)
 IV120 (83.3%)
EGFR ()
 Mutation59 (52.4%)
 Wild type65 (47.6%)
ALK ()
 Positive6 (5.0%)
 Negative115 (95.0%)
PD-L1 (Dako22C3) ()
 <1%53 (41.7%)
 1-49%56 (44.1%)
 ≥50%18 (14.2%)
PD-L1 (SP142 TC/IC) ()
 <1%/<1%85 (64.4%)
 Intermediate33 (25.0%)
 ≥50%/>10%14 (10.6%)
PD-L1 (Dako28-8) ()
 <1%54 (49.1%)
 1-49%42 (38.2%)
 ≥50%14 (12.7%)

NSCLC: non-small cell lung cancer; TC: tumor cells; IC: immune cells.