PD-L1 Immunohistochemistry Comparability and Their Correlation with Clinical Characteristics in NSCLC

Table 2

Overall agreement between assays (>1%).

Reference	Comparison	of comparison	TP	FN	FP	TN	Sensitivity	Specificity	Agreement	κ
Dako22C3	SP142	115	29	38	5	43	43.3%	89.6%	62.6%	0.251
	Dako28-8	107	47	12	7	41	79.7%	85.4%	82.2%	0.645
SP142	Dako22C3	115	29	5	38	43	85.3%	53.1%	62.6%	0.299
	Dako28-8	109	21	7	34	47	75.0%	58.0%	62.4%	0.251
Dako28-8	Dako22C3	107	47	7	12	41	87.0%	77.4%	82.2%	0.645
	SP142	109	21	34	7	47	38.2%	87.0%	62.4%	0.299

TP: true positive; TN: true negative; FP: false positive; FN: false negative; TC: tumor cells; IC: immune cells. SP142 was scored by . Cohen’s kappa coefficient (κ).