PD-L1 Immunohistochemistry Comparability and Their Correlation with Clinical Characteristics in NSCLC

Table 3

Overall agreement between assays (>50%).

Reference	Comparison	of comparison	TP	FN	FP	TN	Sensitivity	Specificity	Agreement	κ
Dako22C3	SP142	115	8	8	2	97	50.0%	98.0%	91.3%	0.569
	Dako28-8	107	8	3	6	90	72.7%	93.8%	91.6%	0.593
SP142	Dako22C3	115	8	2	8	97	80.0%	92.4%	91.3%	0.569
	Dako28-8	109	7	2	7	94	77.8%	93.1%	91.8%	0.565
Dako28-8	Dako22C3	107	8	6	3	90	57.1%	96.8%	91.6%	0.593
	SP142	109	7	7	2	94	50.0%	97.9%	91.8%	0.565

TP: true positive; TN: true negative; FP: false positive; FN: false negative; TC: tumor cells; IC: immune cells. SP142 was scored by . Cohen’s kappa coefficient (κ).