Evaluation of the Potential Prognostic Value of Tumor Budding in Laryngeal Carcinoma by Conventional and Immunohistochemical Staining

Table 4

Backward multivariate Cox regression for evaluating the effect of prognostic histopathologic parameters and tumor budding on progression-free survival.

	HR		Sig.	95% confidence interval for HR
				Lower	Upper
Node stage	11.015	0.018	S	1.515	80.076
Vascular invasion	11.847	0.0001	HS	3.289	42.673
Budding	9.337	0.007	HS	1.829	47.668

Reference no/mild.