MicroRNA-342 Promotes the Malignant-Like Phenotype of Endometrial Stromal Cells via Regulation of Annexin A2

Figure 2

miR-342 promotes the malignant-like phenotype of endometrial stromal cells. The endometrial stromal cells were treated with miR-342 mimic or miR-342 inhibitor. (a) The transfection efficiency of miR-342 mimic or miR-342 inhibitor validated using RT-qPCR. (b) Cell proliferation determined using CCK-8. (c) Cell migration assessed using Transwell migration assay. (d) Cell invasion assessed using Transwell invasion assay. (e) Cell apoptosis determined using flow cytometry. vs. NC mimic; ^#vs. NC inhibitor. All data, representative of three independent experiments in triplicate, are shown as . Unpaired -test was adopted to analyze the differences between two experimental groups. Two-way ANOVA, followed by Tukey’s multiple comparison test, was performed to test data among multiple groups. RT-qPCR: reverse transcription quantitative polymerase chain reaction; miR: microRNA; CCK8: cell counting kit-8; NC: negative control; ANOVA: analysis of variance.

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