Research Article

Hypoxia Enhances Activity and Malignant Behaviors of Colorectal Cancer Cells through the STAT3/MicroRNA-19a/PTEN/PI3K/AKT Axis

Figure 7

The STAT3/miR-19a/PTEN axis affects CRC malignancy in vivo: (a) volume of the xenograft tumors in nude mice (#&, two-way ANOVA); (b) weight of the xenograft tumors in nude mice (#&, two-way ANOVA); (c) number of metastatic nodules in murine liver tissues examined by HE staining (#&, two-way ANOVA). in each group. Compared to the hypoxia + STAT3-NC group; #compared to the si-STAT3 + miR-19a control group; &compared to miR-19a mimic + PTEN-NC group.
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