Pannexin1: Role as a Sensor to Injury Is Attenuated in Pretype 2 Corneal Diabetic Epithelium

Figure 1

Pannexin1 localization in B6 control and DiO corneal epithelium. (a) Representative confocal immunofluorescent images of pannexin1 in unwounded and wounded corneas: 2, 8, and 20 hrs postepithelial debridement. Dotted line indicates the leading edge. Bar equals 25 microns. (b) Enlarged immunofluorescent images of the rectangular boxes in (a) (20 hrs), which show the cell morphology back from the leading edge. Asterisks () mark representative cells in both B6 control and DiO ~6 cells back from the leading edge. Note the elongation of the cell in DiO. Bar equals 10 microns. is a minimum of 3 independent experiments.

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