Pannexin1: Role as a Sensor to Injury Is Attenuated in Pretype 2 Corneal Diabetic Epithelium

Figure 2

Pannexin1 mediates corneal epithelial sheet migration. Representative images of B6 control corneas (in the presence of 10Panx or a scrambled control (control) peptide) wounded, incubated for 2 hrs in medium, fixed, and then stained with rhodamine phalloidin. The inset highlights the differences in actin at the leading edge and demonstrates coalescence of actin in the 10Panx treated corneas. Bar equals 30 microns. is a minimum of 3 independent experiments.