Curcumin Alleviates Oxygen-Glucose-Deprivation/Reperfusion-Induced Oxidative Damage by Regulating miR-1287-5p/LONP2 Axis in SH-SY5Y Cells

<div>Cur alleviates OGD/R-induced SH-SY5Y cell damage, upregulates miR-1287-5p expression, and downregulates LONP2 expression in SH-SY5Y cells. (a) CCK-8 assay was performed to assess the viability of SH-SY5Y cells. Flow cytometry was performed to detect (b) apoptosis, (c) ROS production, and (d) mitochondrial membrane potential in SH-SY5Y cells. (e) qRT-PCR was performed to detect miR-1287-5p expression in SH-SY5Y cells. (f) Western blot was performed to detect LONP2 expression in SH-SY5Y cells. 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Analytical Cellular Pathology

fig3

Figure 3

Figure 3: Curcumin Alleviates Oxygen-Glucose-Deprivation/Reperfusion-Induced Oxidative Damage by Regulating miR-1287-5p/LONP2 Axis in SH-SY5Y Cells 