Histone Deacetylation Regulated by KDM1A to Suppress DACT1 in Proliferation and Migration of Cervical Cancer

Figure 4

KDM1A negatively regulates DACT1 in cervical cancer cells. (a) STING predicted the interaction between KDM1A and HDAC1; (b) UCSC analysis showed the elevated signals in the prompter of HDAC1 after histone 3 deacetylation; (c) CoIP identified the interaction between KDM1A and DACT1; (d) the deacetylation of histone 3 was measured by western blot; (e) in HeLa and SiHa cells, KDM1A knockdown on mRNA expression level of DACT1; (f, g) in HeLa and SiHa cells, KDM1A knockdown on protein expression level of DACT1. and , compared with the control group.

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