Research Article
GRHL3 Promotes Tumor Growth and Metastasis via the MEK Pathway in Colorectal Cancer
Table 1
Correlation analysis of GRHL3 expression and clinical characteristics of patients with CRC.
| Feature | | GRHL3 | | | Low or no expression | High expression | | |
| Gender | | | | | | Male | 63 | 24 | 39 | 0.324 | 0.569 | Female | 37 | 12 | 25 | | | Age (years) | | | | | | ≤60 | 40 | 16 | 24 | 0.463 | 0.496 | >60 | 60 | 20 | 40 | | | Tumor size (cm) | | | | | | <5 | 50 | 23 | 27 | 4.340 | 0.037 | ≥5 | 50 | 13 | 37 | | | Differentiation | | | | | | Well | 29 | 11 | 18 | 0.113 | 0.945 | Middle | 55 | 19 | 36 | | | Poor | 16 | 6 | 10 | | | TNM stage | | | | | | I | 15 | 7 | 8 | 9.603 | 0.022 | II | 34 | 18 | 16 | | | III | 38 | 8 | 30 | | | IV | 13 | 3 | 10 | | | T stage | | | | | | T1+2 | 26 | 14 | 12 | 4.857 | 0.028 | T3+4 | 74 | 22 | 52 | | | N stage | | | | | | N0 | 53 | 26 | 27 | 8.490 | 0.014 | N1 | 31 | 6 | 25 | | | N2 | 16 | 4 | 12 | | | M stage | | | | | | M0 | 87 | 33 | 54 | 0.534 | 0.465 | M1 | 13 | 3 | 10 | | |
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