Research Article

MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway

Figure 2

Knockdown of MMP-9 suppresses OSCC cell proliferation in the nude mouse tongue-xenografted model. (a, b) Expression of MMP-9 in CAL27- or SCC15-transfected cells of nude mouse tongue-xenografted tumors by IHC, respectively. (c, d) Cell proliferation is suppressed by MMP-9/shRNA transfection as shown by Ki67-positive cells. All data are shown as the . , compared with the control group.
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