MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway

<div>Knockdown of MMP-9 suppressed OSCC cell interactions between endothelial cells and xenografted tumor angiogenesis. (a) MMP-9/shRNA transfection suppresses microvascular density (MVD) by IHC. (b) Knockdown of MMP-9 could decrease cell adhesion to endothelial cells by the adhesion assay. (c) Knockdown of MMP-9 could decrease cell transendothelial migration between endothelial cells. 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Analytical Cellular Pathology

fig3

Figure 3

Figure 3: MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway 

Figure 3 | MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway 