MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway

<div>Knockdown of MMP-9 suppresses RhoC, Src, and F-actin expression <i>in vitro</i>. (a) RNA expression of RhoC and Src by RT-PCR in CAL27-transfected cells. (b) Protein expression of RhoC and Src by western blotting in CAL27-transfected cells. (c) Knockdown of MMP-9 suppresses RhoC expression by immunocytochemistry. (d) MMP-9/shRNA transfection decreased phalloidin staining by immunofluorescence. 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Analytical Cellular Pathology

fig8

Figure 8

Figure 8: MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway 

Figure 8 | MMP-9 Knockdown Inhibits Oral Squamous Cell Carcinoma Lymph Node Metastasis in the Nude Mouse Tongue-Xenografted Model through the RhoC/Src Pathway 