A Novel 8-Gene Prognostic Signature for Survival Prediction of Uveal Melanoma

Figure 4

Survival analysis, prognostic performance, and clinical utility of UMPS in the training cohort. (a) Risk score distribution of the training cohort. (b) Survival overview. (c) Heatmap showing the expression of the 8 genes in the low-risk and high-risk groups. (d) Survival curve of the low-risk and high-risk groups by Kaplan-Meier survival analysis. The high-risk group had worse metastasis-free survival than the low-risk group. (e, f) Time-dependent receiver operating characteristic (ROC) analysis for comparing the performance of UMPS with the clinicopathological factors. The AUC of UMPS was higher than the single clinicopathological factor in prediction 3-y and 5-y metastasis-free survival.

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