miR-486 Promotes the Invasion and Cell Cycle Progression of Ovarian Cancer Cells by Targeting CADM1

Figure 2

Interference with miR-486 expression inhibits the biological function of OC cells. (a) CCK-8 to detect the cell viability of SKOV3 after transfection with NC inhibitor and miR-486 inhibitor; (b) colony formation assay to detect the number of colonies of SKOV3 after transfection with NC inhibitor and miR-486 inhibitor; (c) Transwell assay to detect the invasion of SKOV3 after transfection with NC inhibitor and miR-486 inhibitor; (d, e) FCM to detect the apoptosis and cell cycle of SKOV3 after transfection with NC inhibitor and miR-486 inhibitor; (f)Western blot to detect the expression levels of cell cycle-related proteins p21, CyclinD1, CyclinE, and CDK6. and vs. the in-NC group.

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