Expression and Significance of AQP3 in Cutaneous Lesions

Table 1

Summary of immunohistochemistry for AQP3 in skin lesions.

			Absent	Focal	Intermediate	Diffuse
Nonneoplastic lesions	Seborrheic keratosis	14	0	0	0	14
	Verruca vulgaris	16	0	0	0	16
	Sebaceous hyperplasia	13	0	0	0	13
	Molluscum contagiosum	5	0	0	0	5
	Nevocellular nevus	26	18	8	0	0
Benign tumors	Hidradenoma	7	0	0	0	7
	Eccrine poroma	7	1	0	0	6
	Sebaceoma	16	0	4	4	8
	Sebaceous adenoma	10	0	0	0	10
Premalignant lesion and malignant tumors	Solar keratosis	24	0	0	0	24
	Bowen’s disease	26	0	2	0	24
	Squamous cell carcinoma	43	0	3	7	33
	Basal cell carcinoma	32	32	0	0	0
	Paget’s disease	16	0	0	0	16
	Sebaceous carcinoma	9	9	0	0	0
	Apocrine carcinoma	19	0	0	3	16
	Malignant melanoma	28	28	0	0	0

Absent, negative; mild, focal (1 to 9% of cells); moderate, intermediate (10 to 50%); diffuse (more than 50%).