The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia

<div>Oxidative stress-induced apoptosis accompanied with autophagy in microglia. Apoptosis was assayed in microglia and OGD/R-induced microglia, and the autophagy inhibitor 3MA and autophagy agonist RAPA were involved. Apoptosis was measured using both TUNEL staining (×800) (a) and JC-1 assay by flow cytometry (b). The apoptosis-related protein of caspase 3 was also detected using the ELISA kit (c). The mRNA expression of caspase 1 was detected using qPCR (d). 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Analytical Cellular Pathology

fig2

Figure 2

Figure 2: The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia 