| | Compd. | Target | U251 (GI50,nM) | U87 MG (GI50, nM) |
| | Abiraterone | CYP17 | >10,000 | >10,000 | | Alectinib | ALK | >10,000 | 3427 | | Afatinib | EGFR/HER2 | 1733 | 1413 | | Anlotinib | VEGFR/PDGFR/FGFR/Kit | >10,000 | 2513 | | Apatinib | VEGRF2 | >10,000 | >10,000 | | Axitinib | KIT/PDGFR/VEGRFR | >10,000 | 2319 | | Brigatinib | ALK | >10,000 | 6857 | | Bortezomib | Proteasome | 40.61 | 0.7 | | Bosutinib | ABL | >10,000 | >10,000 | | Brivanib | BRAF/KIT/PDGFR/RET/VEGFR | >10,000 | >10,000 | | Cabozantinib | FLT3/KIT/MET/RET/VEGFR | >10,000 | >10,000 | | Cediranib | PDGFR/VEGFR | 9932 | >10,000 | | Ceritinib | ALK?ROS1 | 4728 | 4654 | | Chidamide | HDAC | 9010 | 3785 | | Cobimetinib | BRAF | 6291 | 718.6 | | Dabrafenib | BRAF | >10,000 | >10,000 | | Everolimus | mTOR | >10,000 | >10,000 | | Dacomitnib | EGFR | 7057 | 4849 | | Dasatinib | ABL | >10,000 | >10,000 | | Dovitinib | FLT3/KIT | 7373 | 524.6 | | Erlotinib | EGFR | 1505 | 713.4 | | Larotrectinib | NTRK | >10,000 | >10,000 | | Levatinib | VEGFR2 | 4627 | >10,000 | | Neratinib | EGFR/HER2 | 1810 | 648.4 | | Nilotinib | ABL | 9827 | 3251 | | Nintedanib | VEGFR/FGRF/PDGFR | 6524 | 4481 | | Niraparib | BRCA1/BRCA2 | >10,000 | 617.1 | | Olaparib | BRCA1/BRCA2 | >10,000 | >10,000 | | Osimertinib | EGFR | 4041 | 8861 | | Palbociclib | CDK4, CDK6 | 5252 | 1615 | | Pamiparib | PARP1/PARP2 | >10,000 | 453.7 | | Ponatinib | ABL | 233.6 | 106.7 | | Pyrotinib | EGFR/HER2 | 2024 | >10,000 | | Regorafenib | KIT/VEGFR/PDGFR/RAF/RET | >10,000 | 7954 | | Ribociclib | CDK4/CDK6 | >10,000 | >10,000 | | Romidepsin | HDAC | >10,000 | >10,000 | | Rucaparib | BRCA1/BRCA2 | >10,000 | >10,000 | | Sirolimus | mTOR | >10,000 | >10,000 | | Sorafenib | KIT/VEGFR/PDGFR/RAF | >10,000 | >10,000 | | Sunitinib | PDGFR/VEGFR/KIT/FLT3/RET | 3069 | 1408 | | Temsirolimus | mTOR | >10,000 | 809.7 | | Thalidomide | CRBN | >10,000 | 991.7 | | Tofacitinib | JAK1/JAK3 | >10,000 | >10,000 | | Trametinib | BRAF/MEK1/MEK2 | 7244 | 3311 | | Vandetanib | EGFR/RET/VEGFR2 | 2345 | 5183 | | Veliparib | PARP1/PARP2 | 7561 | >10,000 | | Vemurafenib | BRAF | >10,000 | >10,000 | | Vorinostat | HDAC | 935.9 | 1251 | | Idelalisib | PI3K | >10,000 | >10,000 |
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