KIF26B Is Overexpressed in Medulloblastoma and Promotes Malignant Progression by Activating the PI3K/AKT Pathway

Figure 4

(a) Genes highly correlated with KIF26B expression were analyzed using KEGG enrichment analysis. The PI3K-Akt signal pathway ranks first. (b) Western blot was used to detect the expression of key proteins in the PI3K-AKT signaling pathway after knocking down KIF26B. (c) Western blot was used to detect the expression of phosphorylated AKT after knocking down KIF26B and adding PI3K pathway activator 740 Y-P with concentration of 20 μM. (d, e, and f) After adding the PI3K pathway activator 740 Y-P (20 μM), the proliferation (d), migration (e), and cell cycle (F) of DAOY cells were observed again.

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