Deciphering a Novel Necroptosis-Related miRNA Signature for Predicting the Prognosis of Clear Cell Renal Carcinoma

Figure 6

Exploration and functional enrichment analysis of the miRNAs target genes. (a) Venn diagram of target genes for six miRNAs from NRM signature based on miRDB, miRTarBase, and TargetScan. (b) Dot plot showing the results of gene ontology (GO) enrichment analysis of 392 potential target genes differentially expressed between tumor samples and normal samples. (c) Circle network plot showing the relationships between the top five enriched pathways of Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis and their associated target genes. (d) Bar plot showing the results of KEGG enrichment analysis. Construction of miRNA–mRNA interaction network and identification of hub genes.

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