Synergistic Antitumor Effects of Anlotinib Combined with Oral 5-Fluorouracil/S-1 via Inhibiting Src/AKT Signaling Pathway in Small-Cell Lung Cancer

<div>Anlotinib combined with 5-FU induced cell cycle arrest in the H446 cells using cell cycle kit. (a) The H446 cells were treatment with anlotinib (5 <i>μ</i>M) and 5-FU (10 <i>μ</i>M) or combination of both for 24 h. (b) The cell cycle rate (%) including G1\G0, S and G2\M. All experiments were repeated three times. 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Analytical Cellular Pathology

fig3

Figure 3

Figure 3: Synergistic Antitumor Effects of Anlotinib Combined with Oral 5-Fluorouracil/S-1 via Inhibiting Src/AKT Signaling Pathway in Small-Cell Lung Cancer 

Figure 3 | Synergistic Antitumor Effects of Anlotinib Combined with Oral 5-Fluorouracil/S-1 via Inhibiting Src/AKT Signaling Pathway in Small-Cell Lung Cancer 