Research Article

circ_ZFR Is Linked to Paclitaxel Resistance in Cervical Cancer via miR-944 Sponging and IL-10 Upregulation

Figure 4

The targeting of IL-10 in PTX-resistant CC cells results in the overexpression of miR-944 and elevates PTX sensitivity. (a, b) The significant interaction sites between miR-944 and IL-10 determined by the DLR assay. (c) miR-944 expression was assessed via qRT-PCR. (d, f, j) The data obtained from qRT-PCR analysis to examine the expression level of IL-10. (e, g, k) The ELISA assay data to detect the expression level of IL-10. (h) The qRT-PCR evaluations for IL-10 level in CC tissues. (i) The correlation between IL-10 and miR-944 was estimated by Spearman’s correlation coefficient analysis. (l) The values of PTX in HeLa/PTX and SiHa/PTX cells. .
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