miR-145-3p Hampers the Malignant Progression of Esophageal Carcinoma via CXCL5 Downregulation

<div>miR-145-3p modulates cell progression in EC through targeting CXCL5. (a, b) CXCL5 mRNA and protein expression in different treatment groups (miR-NC+oe-NC, miR-NC+oe-CXCL5, and miR-mimics+oe-CXCL5). (c) The proliferation of EC9706 cells in each treatment group. (d) The invasive ability of EC9706 cells in each treatment group (100x). (e) The migratory ability of EC9706 cells in each treatment group (40x). (f) The apoptosis rate of EC9706 cells in each treatment group. When the miR-NC+oe-NC group was compared with the miR-NC+oe-CXCL5 group, miR-NC+oe-NC was the control; when the miR-NC+oe-CXCL5 group was compared with the miR-mimics+oe-CXCL5 group, miR-mimics+oe-CXCL5 was the control. <span class="nowrap"><svg height="13.806pt" id="M50" style="vertical-align:-3.429399pt" version="1.1" viewbox="-0.0498162 -10.3766 145.878 13.806" width="145.878pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 275 262C225 236 198 227 145 220C133 201 125 177 126 158C141 148 167 143 189 144C222 186 243 205 290 236C288 179 282 152 262 102C272 82 289 63 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Analytical Cellular Pathology

fig5

Figure 5

Figure 5: miR-145-3p Hampers the Malignant Progression of Esophageal Carcinoma via CXCL5 Downregulation 