LINC02389/miR-7-5p Regulated Cisplatin Resistance of Non-Small-Cell Lung Cancer via Promoting Oxidative Stress

Figure 5

(a) miR-7-5p expression in LINC02389 knocked down A549 cell line. (b) miR-7-5p expression in LINC02389 knocked down HCC827 cell line. (c) Dual luciferase activity assay to test the binding of LINC02389 to miR-7-5p in A549. (d) Dual luciferase activity assay to test the binding of LINC02389 to miR-7-5p in HCC827. (e) RNA pull-down assay to test the interaction between miR-7-5p and LINC02389 in A549. (f) RNA pull-down assay to test the interaction between miR-7-5p and LINC02389 in HCC827. (g) miR-7-5p knockdown could reverse the effect of LINC02389 knockdown on IC50 of A549-R to cisplatin.

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