|
| Tumor entity | On TMA () | PR immunostaining |
| Analyzable () | Negative (%) | Weak (%) | Moderate (%) | Strong (%) |
|
| Tumors of the skin () | Pilomatrixoma | 35 | 34 | 100.0 | 0.0 | 0.0 | 0.0 |
| Basal cell carcinoma | 88 | 82 | 100.0 | 0.0 | 0.0 | 0.0 |
| Benign nevus | 29 | 29 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the skin | 90 | 90 | 100.0 | 0.0 | 0.0 | 0.0 |
| Malignant melanoma | 46 | 46 | 100.0 | 0.0 | 0.0 | 0.0 |
| Malignant melanoma lymph node metastasis | 86 | 84 | 100.0 | 0.0 | 0.0 | 0.0 |
| Merkel cell carcinoma | 46 | 45 | 100.0 | 0.0 | 0.0 | 0.0 |
|
| Tumors of the head and neck () | Squamous cell carcinoma of the larynx | 60 | 54 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the pharynx | 60 | 59 | 100.0 | 0.0 | 0.0 | 0.0 |
| Oral squamous cell carcinoma (floor of the mouth) | 80 | 80 | 100.0 | 0.0 | 0.0 | 0.0 |
| Warthin tumor of the parotid gland | 55 | 53 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma, NOS (papillary cystadenocarcinoma) | 14 | 11 | 100.0 | 0.0 | 0.0 | 0.0 |
| Salivary duct carcinoma | 15 | 13 | 100.0 | 0.0 | 0.0 | 0.0 |
| Acinic cell carcinoma of the salivary gland | 181 | 135 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma NOS of the salivary gland | 109 | 81 | 97.5 | 0.0 | 1.2 | 1.2 |
| Adenoid cystic carcinoma of the salivary gland | 180 | 126 | 100.0 | 0.0 | 0.0 | 0.0 |
| Basal cell adenocarcinoma of the salivary gland | 25 | 21 | 100.0 | 0.0 | 0.0 | 0.0 |
| Basal cell adenoma of the salivary gland | 86 | 66 | 100.0 | 0.0 | 0.0 | 0.0 |
| Epithelial-myoepithelial carcinoma of the salivary gland | 53 | 52 | 100.0 | 0.0 | 0.0 | 0.0 |
| Mucoepidermoid carcinoma of the salivary gland | 343 | 327 | 99.7 | 0.0 | 0.3 | 0.0 |
| Myoepithelial carcinoma of the salivary gland | 21 | 17 | 94.1 | 0.0 | 5.9 | 0.0 |
| Myoepithelioma of the salivary gland | 11 | 10 | 100.0 | 0.0 | 0.0 | 0.0 |
| Oncocytic carcinoma of the salivary gland | 12 | 8 | 100.0 | 0.0 | 0.0 | 0.0 |
| Polymorphous adenocarcinoma, low grade, of the salivary gland | 41 | 34 | 100.0 | 0.0 | 0.0 | 0.0 |
| Pleomorphic adenoma of the salivary gland | 53 | 41 | 100.0 | 0.0 | 0.0 | 0.0 |
|
| Tumors of the lung, pleura, and thymus () | Adenocarcinoma of the lung | 196 | 191 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the lung | 80 | 75 | 100.0 | 0.0 | 0.0 | 0.0 |
| Small cell carcinoma of the lung | 16 | 16 | 87.5 | 6.3 | 6.3 | 0.0 |
| Mesothelioma, epitheloid | 39 | 30 | 100.0 | 0.0 | 0.0 | 0.0 |
| Mesothelioma, other types | 76 | 70 | 100.0 | 0.0 | 0.0 | 0.0 |
|
| Tumors of the female genital tract () | Squamous cell carcinoma of the vagina | 78 | 74 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the vulva | 130 | 123 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the cervix | 129 | 126 | 99.2 | 0.8 | 0.0 | 0.0 |
| Adenocarcinoma of the cervix | 21 | 21 | 90.5 | 4.8 | 4.8 | 0.0 |
| Endometrioid endometrial carcinoma | 236 | 197 | 33.5 | 21.8 | 13.7 | 31.0 |
| Endometrial serous carcinoma | 82 | 68 | 79.4 | 14.7 | 2.9 | 2.9 |
| Carcinosarcoma of the uterus | 48 | 41 | 87.8 | 4.9 | 0.0 | 7.3 |
| Endometrial carcinoma, high grade, G3 | 13 | 12 | 83.3 | 8.3 | 0.0 | 8.3 |
| Endometrial clear cell carcinoma | 8 | 6 | 100.0 | 0.0 | 0.0 | 0.0 |
| Endometrioid carcinoma of the ovary | 110 | 92 | 38.0 | 18.5 | 14.1 | 29.3 |
| Serous carcinoma of the ovary | 559 | 520 | 67.9 | 22.1 | 4.2 | 5.8 |
| Mucinous carcinoma of the ovary | 96 | 77 | 94.8 | 0.0 | 0.0 | 5.2 |
| Clear cell carcinoma of the ovary | 50 | 45 | 88.9 | 6.7 | 2.2 | 2.2 |
| Carcinosarcoma of the ovary | 47 | 44 | 65.9 | 22.7 | 6.8 | 4.5 |
| Granulosa cell tumor of the ovary | 37 | 37 | 18.9 | 29.7 | 29.7 | 21.6 |
| Leydig cell tumor of the ovary | 4 | 4 | 50.0 | 50.0 | 0.0 | 0.0 |
| Sertoli cell tumor of the ovary | 1 | 1 | 100.0 | 0.0 | 0.0 | 0.0 |
| Sertoli Leydig cell tumor of the ovary | 3 | 3 | 33.3 | 66.7 | 0.0 | 0.0 |
| Steroid cell tumor of the ovary | 3 | 3 | 100.0 | 0.0 | 0.0 | 0.0 |
| Brenner tumor | 41 | 40 | 95.0 | 0.0 | 0.0 | 5.0 |
|
| Tumors of the breast () | Invasive breast carcinoma of no special type | 1764 | 1605 | 42.9 | 10.7 | 10.7 | 35.8 |
| Lobular carcinoma of the breast | 363 | 302 | 43.0 | 9.9 | 9.6 | 37.4 |
| Medullary carcinoma of the breast | 34 | 33 | 87.9 | 3.0 | 3.0 | 6.1 |
| Tubular carcinoma of the breast | 29 | 23 | 17.4 | 8.7 | 8.7 | 65.2 |
| Mucinous carcinoma of the breast | 65 | 51 | 23.5 | 7.8 | 7.8 | 60.8 |
| Phyllodes tumor of the breast | 50 | 37 | 27.0 | 0.0 | 18.9 | 54.1 |
|
| Tumors of the digestive system () | Adenomatous polyp, low-grade dysplasia | 50 | 50 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenomatous polyp, high-grade dysplasia | 50 | 50 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma of the colon | 2482 | 2146 | 99.9 | 0.0 | 0.0 | 0.0 |
| Gastric adenocarcinoma, diffuse type | 176 | 150 | 100.0 | 0.0 | 0.0 | 0.0 |
| Gastric adenocarcinoma, intestinal type | 174 | 157 | 100.0 | 0.0 | 0.0 | 0.0 |
| Gastric adenocarcinoma, mixed type | 62 | 49 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma of the esophagus | 83 | 83 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the esophagus | 75 | 75 | 100.0 | 0.0 | 0.0 | 0.0 |
| Squamous cell carcinoma of the anal canal | 89 | 88 | 100.0 | 0.0 | 0.0 | 0.0 |
| Cholangiocarcinoma | 50 | 50 | 100.0 | 0.0 | 0.0 | 0.0 |
| Gallbladder adenocarcinoma | 31 | 31 | 100.0 | 0.0 | 0.0 | 0.0 |
| Gallbladder klatskin tumor | 41 | 39 | 100.0 | 0.0 | 0.0 | 0.0 |
| Hepatocellular carcinoma | 300 | 299 | 100.0 | 0.0 | 0.0 | 0.0 |
| Ductal adenocarcinoma of the pancreas | 612 | 505 | 97.8 | 1.0 | 0.6 | 0.6 |
| Pancreatic/ampullary adenocarcinoma | 89 | 75 | 100.0 | 0.0 | 0.0 | 0.0 |
| Acinar cell carcinoma of the pancreas | 16 | 15 | 100.0 | 0.0 | 0.0 | 0.0 |
| Gastrointestinal stromal tumor (GIST) | 50 | 49 | 100.0 | 0.0 | 0.0 | 0.0 |
|
| Tumors of the urinary system () | Noninvasive papillary urothelial carcinoma, pTa G2 low grade | 177 | 170 | 100.0 | 0.0 | 0.0 | 0.0 |
| Noninvasive papillary urothelial carcinoma, pTa G2 high grade | 141 | 135 | 100.0 | 0.0 | 0.0 | 0.0 |
| Noninvasive papillary urothelial carcinoma, pTa G3 | 219 | 195 | 100.0 | 0.0 | 0.0 | 0.0 |
| Urothelial carcinoma, pT2-4 G3 | 735 | 636 | 99.7 | 0.0 | 0.0 | 0.3 |
| Squamous cell carcinoma of the bladder | 22 | 22 | 100.0 | 0.0 | 0.0 | 0.0 |
| Small cell neuroendocrine carcinoma of the bladder | 23 | 23 | 95.7 | 4.3 | 0.0 | 0.0 |
| Sarcomatoid urothelial carcinoma | 25 | 23 | 100.0 | 0.0 | 0.0 | 0.0 |
| Urothelial carcinoma of the kidney pelvis | 62 | 61 | 98.4 | 1.6 | 0.0 | 0.0 |
| Clear cell renal cell carcinoma | 1287 | 1179 | 99.9 | 0.1 | 0.0 | 0.0 |
| Papillary renal cell carcinoma | 368 | 329 | 99.7 | 0.3 | 0.0 | 0.0 |
| Clear cell (tubulo) papillary renal cell carcinoma | 26 | 24 | 95.8 | 0.0 | 4.2 | 0.0 |
| Chromophobe renal cell carcinoma | 170 | 153 | 95.4 | 3.3 | 0.0 | 1.3 |
| Oncocytoma | 257 | 231 | 93.1 | 6.5 | 0.4 | 0.0 |
|
| Tumors of the male genital organs () | Adenocarcinoma of the prostate, Gleason | 83 | 83 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma of the prostate, Gleason | 80 | 80 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma of the prostate, Gleason | 85 | 85 | 100.0 | 0.0 | 0.0 | 0.0 |
| Adenocarcinoma of the prostate (recurrence) | 258 | 257 | 99.6 | 0.4 | 0.0 | 0.0 |
| Small cell neuroendocrine carcinoma of the prostate | 19 | 18 | 83.3 | 16.7 | 0.0 | 0.0 |
| Seminoma | 621 | 586 | 100.0 | 0.0 | 0.0 | 0.0 |
| Embryonal carcinoma of the testis | 50 | 45 | 100.0 | 0.0 | 0.0 | 0.0 |
| Leydig cell tumor of the testis | 30 | 30 | 63.3 | 33.3 | 3.3 | 0.0 |
| Sertoli cell tumor of the testis | 2 | 1 | 0.0 | 100.0 | 0.0 | 0.0 |
| Sex cord stromal tumor of the testis | 1 | 1 | 0.0 | 0.0 | 100.0 | 0.0 |
| Spermatocytic tumor of the testis | 1 | 1 | 100.0 | 0.0 | 0.0 | 0.0 |
| Yolk sac tumor | 50 | 44 | 100.0 | 0.0 | 0.0 | 0.0 |
| Teratoma | 50 | 41 | 95.1 | 0.0 | 0.0 | 4.9 |
| Squamous cell carcinoma of the penis | 80 | 78 | 100.0 | 0.0 | 0.0 | 0.0 |
|
| Tumors of endocrine organs () | Adenoma of the thyroid gland | 114 | 112 | 92.9 | 4.5 | 2.7 | 0.0 |
| Papillary thyroid carcinoma | 392 | 379 | 89.4 | 9.0 | 1.1 | 0.5 |
| Follicular thyroid carcinoma | 154 | 151 | 88.7 | 5.3 | 3.3 | 2.6 |
| Medullary thyroid carcinoma | 111 | 108 | 79.6 | 16.7 | 1.9 | 1.9 |
| Parathyroid gland adenoma | 43 | 42 | 100.0 | 0.0 | 0.0 | 0.0 |
| Anaplastic thyroid carcinoma | 45 | 43 | 97.7 | 2.3 | 0.0 | 0.0 |
| Adrenal cortical adenoma | 50 | 44 | 95.5 | 2.3 | 0.0 | 2.3 |
| Adrenal cortical carcinoma | 26 | 26 | 88.5 | 11.5 | 0.0 | 0.0 |
| Phaeochromocytoma | 50 | 49 | 100.0 | 0.0 | 0.0 | 0.0 |
| Appendix, neuroendocrine tumor (NET) | 22 | 17 | 94.1 | 0.0 | 5.9 | 0.0 |
| Colorectal, neuroendocrine tumor (NET) | 12 | 11 | 100.0 | 0.0 | 0.0 | 0.0 |
| Ileum, neuroendocrine tumor (NET) | 49 | 49 | 100.0 | 0.0 | 0.0 | 0.0 |
| Lung, neuroendocrine tumor (NET) | 19 | 18 | 100.0 | 0.0 | 0.0 | 0.0 |
| Pancreas, neuroendocrine tumor (NET) | 97 | 94 | 45.7 | 17.0 | 9.6 | 27.7 |
| Colorectal, neuroendocrine carcinoma (NEC) | 12 | 10 | 100.0 | 0.0 | 0.0 | 0.0 |
| Gallbladder, neuroendocrine carcinoma (NEC) | 4 | 4 | 100.0 | 0.0 | 0.0 | 0.0 |
| Pancreas, neuroendocrine carcinoma (NEC) | 14 | 14 | 64.3 | 7.1 | 14.3 | 14.3 |
|
| Tumors of haematopoetic and lymphoid tissues () | Hodgkin lymphoma | 58 | 53 | 100.0 | 0.0 | 0.0 | 0.0 |
| Small lymphocytic lymphoma, B-cell type (B-SLL/B-CLL) | 50 | 44 | 100.0 | 0.0 | 0.0 | 0.0 |
| Diffuse large B cell lymphoma (DLBCL) | 113 | 103 | 100.0 | 0.0 | 0.0 | 0.0 |
| Follicular lymphoma | 88 | 80 | 100.0 | 0.0 | 0.0 | 0.0 |
| T-cell non-Hodgkin lymphoma | 25 | 24 | 100.0 | 0.0 | 0.0 | 0.0 |
| Mantle cell lymphoma | 18 | 17 | 100.0 | 0.0 | 0.0 | 0.0 |
| Marginal zone lymphoma | 16 | 14 | 100.0 | 0.0 | 0.0 | 0.0 |
| Diffuse large B-cell lymphoma (DLBCL) in the testis | 16 | 16 | 100.0 | 0.0 | 0.0 | 0.0 |
| Burkitt lymphoma | 5 | 2 | 100.0 | 0.0 | 0.0 | 0.0 |
|
| Tumors of soft tissue and bone () | Tenosynovial giant cell tumor | 45 | 45 | 100.0 | 0.0 | 0.0 | 0.0 |
| Granular cell tumor | 53 | 45 | 100.0 | 0.0 | 0.0 | 0.0 |
| Leiomyosarcoma | 38 | 37 | 89.2 | 2.7 | 0.0 | 8.1 |
| Liposarcoma | 132 | 130 | 100.0 | 0.0 | 0.0 | 0.0 |
| Malignant peripheral nerve sheath tumor (MPNST) | 13 | 13 | 100.0 | 0.0 | 0.0 | 0.0 |
| Myofibrosarcoma | 26 | 26 | 100.0 | 0.0 | 0.0 | 0.0 |
| Angiosarcoma | 73 | 66 | 100.0 | 0.0 | 0.0 | 0.0 |
| Angiomyolipoma | 91 | 88 | 87.5 | 9.1 | 0.0 | 3.4 |
| Dermatofibrosarcoma protuberans | 21 | 17 | 100.0 | 0.0 | 0.0 | 0.0 |
| Ganglioneuroma | 14 | 14 | 100.0 | 0.0 | 0.0 | 0.0 |
| Kaposi sarcoma | 8 | 5 | 100.0 | 0.0 | 0.0 | 0.0 |
| Neurofibroma | 117 | 104 | 95.2 | 4.8 | 0.0 | 0.0 |
| Sarcoma, not otherwise specified (NOS) | 74 | 70 | 98.6 | 0.0 | 0.0 | 1.4 |
| Paraganglioma | 41 | 41 | 100.0 | 0.0 | 0.0 | 0.0 |
| Ewing sarcoma | 23 | 18 | 100.0 | 0.0 | 0.0 | 0.0 |
| Rhabdomyosarcoma | 6 | 6 | 100.0 | 0.0 | 0.0 | 0.0 |
| Schwannoma | 121 | 112 | 100.0 | 0.0 | 0.0 | 0.0 |
| Synovial sarcoma | 12 | 11 | 100.0 | 0.0 | 0.0 | 0.0 |
| Osteosarcoma | 43 | 39 | 100.0 | 0.0 | 0.0 | 0.0 |
| Chondrosarcoma | 38 | 22 | 100.0 | 0.0 | 0.0 | 0.0 |
| Rhabdoid tumor | 5 | 5 | 100.0 | 0.0 | 0.0 | 0.0 |
|
