Transcription Factor E2F1 Exacerbates Papillary Thyroid Carcinoma Cell Growth and Invasion via Upregulation of LINC00152

Figure 3

LINC00152 overexpression diminishes the repressive role of E2F1 knockdown on PTC cell growth and invasion. (a) Expression patterns of E2F1 and LINC00152 in TPC-1 cells assessed via RT-qPCR. (b) E2F1 expression patterns in TPC-1 cells calculated by Western blot analysis. (c, d) Cell proliferation detected by (c) CCK-8 and (d) colony formation assay. (e) Cell migration and invasion measured through Transwell assay. . Data are expressed as . One-way ANOVA was used to determine statistical significance. Tukey’s multiple comparisons test was applied for post hoc test. ; .

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