Transcription Factor E2F1 Exacerbates Papillary Thyroid Carcinoma Cell Growth and Invasion <i>via</i> Upregulation of LINC00152

<div>E2F1 knockout inhibits PTC tumor growth <i>in vivo</i>. (a) Tumor volume assessment. (b) Images of transplanted tumors in nude mice. (c) Weights of transplanted tumor in nude mice. (d) Expression patterns of LINC00152 and E2F1 mRNA detected by RT-qPCR. (e) Level of E2F1 protein verified through Western blot analysis. (f) Ki67 positive expression patterns measured by immunohistochemical staining. <span class="nowrap"><svg height="8.8423pt" id="M64" style="vertical-align:-0.2064009pt" version="1.1" viewbox="-0.0498162 -8.6359 32.2343 8.8423" width="32.2343pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M822 650H589L583 622C660 617 677 607 674 561C672 534 664 481 647 390L600 137H596L273 650H126L120 622C176 620 194 615 207 594C221 571 225 557 214 504L161 257C141 166 129 112 121 85C108 42 83 30 29 28L23 0H260L266 28C193 33 173 42 176 89C178 122 186 172 202 255L256 527H259L583 -8H612L690 390C708 481 720 535 728 558C744 603 756 619 816 622L822 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,14.542,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z"></path></g><g transform="matrix(.013,0,0,-0.013,25.805,0)"><path d="M137 343C167 482 260 545 321 574C357 591 397 603 429 609L423 641C382 634 335 622 295 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Analytical Cellular Pathology

fig5

Figure 5

Figure 5: Transcription Factor E2F1 Exacerbates Papillary Thyroid Carcinoma Cell Growth and Invasion <i>via</i> Upregulation of LINC00152 

Analytical Cellular Pathology

Transcription Factor E2F1 Exacerbates Papillary Thyroid Carcinoma Cell Growth and Invasion via Upregulation of LINC00152

Figure 5