The Relationship between MACC1/c-Met/Cyclin D1 Axis Expression and Prognosis in ESCC

Figure 1

IHC staining of MACC1, c-Met, and cyclin D1 in ESCC tissues and normal esophageal mucosa. Notes: (a) MACC1-negative expression in normal esophageal tissues (×10); (b) MACC1-negative expression in normal esophageal tissues (×40); (c) MACC1-positive localized in cytoplasm expression in ESCC (×10); (d) MACC1-positive expression in ESCC (×40); (e) c-Met-negative expression in normal esophageal tissues (×10); (f) c-Met-negative expression in normal esophageal tissues (×40); (g) c-Met-positive expression localized in the cell cytoplasm and cell nucleus in ESCC (×10); (h) c-Met-positive expression in ESCC (×40); (i) cyclin D1 expression in mucosal basal lamina cells of normal esophageal tissues (×10); (j) cyclin D1-negative expression in normal esophageal tissues (×40); (k) cyclin D1-positive localized in nucleus expression in ESCC (×10); (l) cyclin D1-positive expression in ESCC (×40). Abbreviations: ESCC: esophageal squamous cell carcinoma; IHC: immunohistochemistry.

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