Incidental Papillary Microcarcinoma and Papillary Thyroid Carcinoma in Multinodular Goiter

Table 2

Patient and tumor characteristic comparison between PMC and PTC.

Characteristics	PMC (^a)	PTC (^a)	-Value
Age (years)
>45	86 (64%)	37 (55%)	0.219^b
≤45	48 (36%)	30 (45%)
Gender
Female	107 (80%)	46 (69%)	0.079^b
Male	27 (20%)	21 (31%)
Localization
Right	69 (51%)	39 (58%)	0.709^c
Left	55 (41%)	24 (36%)
Isthmus	10 (7%)	4 (6%)
Bilaterality
Absent	110 (83%)	47 (70%)	0.041^b
Present	23 (17%)	20 (30%)
Multifocality
Absent	114 (85%)	54 (81%)	0.419^b
Present	20 (15%)	13 (19%)
Tumor size (cm)	0.40 (0.2–0.6)	2.00 (1.50–3.20)	<0.001^b
TGF
Noncapsulated	112 (84%)	27 (40%)	<0.001^b
Encapsulated	22 (16%)	40 (60%)
Extra-thyroidal extension
Absent	127 (95%)	61 (91%)	0.365^c
Present	7 (5%)	6 (9%)
Intra-tumoral lymphocyte
Absent	128 (96%)	61 (91%)	0.220^c
Present	6 (4%)	6 (9%)
Nontumoral lymphocyte
Absent	119 (89%)	59 (88%)	0.875^b
Present	15 (11%)	8 (12%)
Intra-tumoral fibrosis
Absent	122 (91%)	60 (90%)	0.733^b
Present	12 (9%)	7 (10%)
Nontumoral fibrosis
Absent	129 (96%)	61 (91%)	0.185^c
Present	5 (3%)	6 (9%)
Disease stage
pT1	128 (96%)	35 (52%)	<0.001^b
pT2	1 (0.7%)	22 (33%)
pT3	5 (3%)	10 (15%)
TCI
Absent	122 (91%)	46 (69%)	<0.001^b
Present	12 (9%)	21 (31%)
VI			0.012^c
Absent	134 (100%)	63 (94%)
Present	0 (0%)	4 (6.0%)

^an (%); median (25–75%).
^bPearson’s chi-squared test.
^cFisher’s exact test.