Incidental Papillary Microcarcinoma and Papillary Thyroid Carcinoma in Multinodular Goiter

Table 3

Comparison between unilateral and bilateral PTC.

	Bilaterality
Characteristics	Absent, ^a	Present, ^a	-Value
Age (years)
>45	27 (57%)	10 (50%)	0.575^b
≤45	20 (43%)	10 (50%)
Gender
Female	36 (77%)	10 (50%)	0.032^b
Male	11 (23%)	10 (50%)
Tumor size (cm)	2 (1.5–3)	2.55 (1.5–4.12)	0.249^c
TGF
Encapsulated	28 (60%)	12 (60%)	0.974^b
Noncapsulated	19 (40%)	8 (40%)
Extra-thyroidal extension
Absent	44 (94%)	17 (85%)	0.353^d
Present	3 (6%)	3 (15%)
Intra-tumoral lymphocyte
Absent	44 (94%)	17 (85%)	0.353^d
Present	3 (6%)	3 (15%)
Nontumoral lymphocyte
Absent	43 (91%)	16 (80%)	0.226^d
Present	4 (8%)	4 (20%)
Intra-tumoral fibrosis
Absent	41 (87%)	19 (95%)	0.665^d
Present	6 (13%)	1 (5%)
Nontumoral fibrosis
Absent	43 (91%)	18 (90%)	>0.999^d
Present	4 (8%)	2 (10%)
Disease stage
pT1	27 (57%)	8 (40%)	0.090^d
pT2	16 (34%)	6 (30%)
pT3	4 (8%)	6 (30%)
TCI
Absent	31 (66%)	15 (75%)	0.465^b
Present	16 (34%)	5 (25%)
VI
Absent	45 (96%)	18 (90%)	0.577^d
Present	2 (4%)	2 (10%)

^an (%); median (25–75%).
^bPearson’s chi-squared test.
^cMann–Whitney U test.
^dFisher’s exact test.