Incidental Papillary Microcarcinoma and Papillary Thyroid Carcinoma in Multinodular Goiter

Table 4

Comparison between unifocal and multifocal PTC.

	Multifocality
Characteristics	Absent, ^a	Present, ^a	-Value
Age (years)
>45	32 (59%)	5 (38%)	0.176^b
≤45	22 (41%)	8 (62%)
Gender
Female	39 (72%)	7 (54%)	0.317^c
Male	15 (28%)	6 (46%)
Tumor size (cm)	2 (1.50–3.15)	2.50 (1.5–3.5)	0.975^d
TGF
Encapsulated	34 (63%)	6 (46%)	0.267^b
Noncapsulated	20 (37%)	7 (54%)
Extra-thyroidal extension
Absent	48 (89%)	13 (100%)	0.588^c
Present	6 (11%)	0 (0%)
Intra-tumoral lymphocyte
Absent	51 (94%)	10 (77%)	0.082^c
Present	3 (5%)	3 (23%)
Nontumoral lymphocyte
Absent	49 (91%)	10 (77%)	0.179^c
Present	5 (9%)	3 (23%)
Intra-tumoral fibrosis
Absent	48 (89%)	12 (92%)	>0.999^c
Present	6 (11%)	1 (7%)
Nontumoral fibrosis
Absent	50 (93%)	11 (85%)	0.329^c
Present	4 (7%)	2 (15%)
Disease stage
pT1	28 (52%)	7 (54%)	>0.999^c
pT2	18 (33%)	4 (31%)
pT3	8 (15%)	2 (15%)
TCI
Absent	36 (67%)	10 (77%)	0.740^c
Present	18 (33%)	3 (23%)
VI
Absent	50 (93%)	13 (100%)	0.579^c
Present	4 (7%)	0 (0%)

^an (%); median (25–75%).
^bPearson’s chi-squared test.
^cFisher’s exact test.
^dMann Whitney U Test.