Suppression of lncRNA OIP5-AS1 Attenuates Apoptosis and Inflammation, and Promotes Proliferation by Mediating miR-25-3p Expression in Lipopolysaccharide-Induced Myocardial Injury

Figure 6

The regulatory role of OIP5-AS1 on LPS-induced inflammation is associated with miR-25-3p. (a) Relative expression of miR-25-3p in myocardial tissues from LPS-induced rats was determined by qRT-PCR. (b) Relative expression of miR-25-3p in LPS-treated H9C2 cells was determined by qRT-PCR. **versus control. (c) The efficiency of OIP5-AS1 overexpression in H9C2 cells was detected by qRT-PCR. **versus pcDNA-NC. (d and e) The levels of IL-6 and TNF-α in culture supernatants of H9C2 cells were measured by ELISA. **versus control. ^##versus NC. ^&&versus pcDNA-OIP5-AS1.

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