Suppression of lncRNA OIP5-AS1 Attenuates Apoptosis and Inflammation, and Promotes Proliferation by Mediating miR-25-3p Expression in Lipopolysaccharide-Induced Myocardial Injury

<div>MiR-25-3p blocks the NOX4/NF-κB signalling pathway in LPS-treated H9C2 cells. (a) The WT binding site of NOX4 with miR-25-3p was predicted by miRDB and relevant mutant (MUT) sequence. (b) The target relationship between NOX4 and miR-25-3p was validated by luciferase reporter assay. (c) The protein levels of NOX4 and p-NF-κB p65/NF-κB p65 were measured by western blot. **versus control. ##versus LPS blank.</div>

Analytical Cellular Pathology

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Figure 8

Figure 8: Suppression of lncRNA OIP5-AS1 Attenuates Apoptosis and Inflammation, and Promotes Proliferation by Mediating miR-25-3p Expression in Lipopolysaccharide-Induced Myocardial Injury 

Figure 8 | Suppression of lncRNA OIP5-AS1 Attenuates Apoptosis and Inflammation, and Promotes Proliferation by Mediating miR-25-3p Expression in Lipopolysaccharide-Induced Myocardial Injury 