TMEM147 Correlates with Immune Infiltration and Serve as a Potential Prognostic Biomarker in Hepatocellular Carcinoma

Figure 6

Association between the expression of TMEM147 and immune cell infiltration in the HCC microenvironment. (a) and (b) Relationship between TMEM147 expression and infiltration of 24 immune cell types; TMEM147 expression strongly positively associates with infiltrating levels of (c) Th2 cells, (d) TFH cells, (e) NK CD56 bright cells, and (f) macrophages; TMEM147 has a negative correlation with (g) Th17 cells and (h) Tcm cells; immunofluorescence co-staining for NCAM1 and TMEM147 (i), as well as F4/80 and TMEM147 (j) in HCC and paired normal tissues (scale bar, 20 μm).

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