LncRNA AC040162.3 Promotes HCV-Induced T2DM Deterioration through the miRNA-223-3p/NLRP3 Molecular Axis

Figure 4

Identification of targeting relationships. (a) Schematic diagram of the putative binding sites of LncRNA AC040162.3 and miR-223-3p. (b) Validation of the targeting relationship between lncRNA AC040162.3 and miR-223-3p. (c) RT-qPCR analysis of LncRNA AC040162.3. (d) Schematic diagram of the miR-223-3p putative binding sites and mutant site in the 3-UTR of NLRP3 predicted by bioinformatics. (e) Validation of the targeting relationship between miR-223-3p and NLRP3. (f) RT-qPCR analysis of NLRP3. WT: wild-type; MUT: mutant-type. **, ***, vs. NC.

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