Classification of Signature-Based Phenotypes of Aging-Related Genes to Identify Prognostic and Immune Characteristics in HCC

Figure 4

Construction of aging-associated gene-based prognostic model. (a) Differently expressed genes among the three clusters. In total, 139 genes were selected. The red represents risk factor genes, and the blue represents protective roles. (b) The curve of coefficients changes with the value of lambda. (c) The partial likelihood deviance varies with the value of lambda. (d) Distribution of LASSO coefficients of the senescence-related gene signature. (e) mRNA expression of six senescence-related genes. *P < 0.05; **P < 0.01; ***P < 0.001.

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