Selenium Donor Inhibited Hepatitis B Virus Associated Hepatotoxicity via the Apoptosis and Ferroptosis Pathways

Table 2

Serum selenium levels in HBV⁺-HCCs group and CHB group.

Clinical characteristics	CHB group (n = 45)			HBV^+-HCC group (n = 45)
	Se low (n = 22)	Se high (n = 23)	P value	Se low (n = 22)	Se high (n = 23)	P value
Age
>55	8	14	0.100	12	8	0.182
≤55	14	9		10	15
Gender
Male	14	19	0.150	3	6	0.297
Female	8	4		19	17
HBV-DNA positive
Yes	19	17	0.297	17	17	0.793
>10^3 copies/mL
No	3	6		5	6
Anti-HBV treatment
Yes	16	8	0.0108	16	10	0.0471
No	6	15		6	13
Tumor size
>5	–	–	–	14	6	0.0113
≤5	–	–		8	17
Stage
I/II	–	–	–	8	15	0.0529
III/IV	–	–		14	8
Lymphatic metastasis
Yes	–	–	–	14	5	0.0045
No	–	–		8	18